Recombinant Human DYNLT1, GST-tagged

• Cat.No.: DYNLT1-12235H
• Product Overview: Recombinant Human DYNLT1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-113a.a.
• Description: Cytoplasmic dynein is the major motor protein complex responsible for minus-end, microtubule-based motile processes. Each dynein complex consists of 2 heavy chains that have ATPase and motor activities, plus a group of accessory polypeptides. TCTEX1 is a dynein light chain involved in cargo binding (Chuang et al., 2005 [PubMed 15992542]).
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DYNLT1 dynein, light chain, Tctex-type 1 [ Homo sapiens ]
• Official Symbol: DYNLT1
• Synonyms: DYNLT1; dynein, light chain, Tctex-type 1; t complex associated testis expressed 1 like 1 , TCTEL1; dynein light chain Tctex-type 1; T-complex testis-specific protein 1 homolog; t-complex-associated-testis-expressed 1-like 1; CW-1; TCTEL1; tctex-1; MGC111571
• Gene ID: 6993
• mRNA Refseq: NM_006519
• Protein Refseq: NP_006510
• MIM: 601554
• UniProt ID: P63172
• Chromosome Location: 6q25.2-q25.3
• Pathway: Lissencephaly gene (LIS1) in neuronal migration and development, organism-specific biosystem; Neurotrophic factor-mediated Trk receptor signaling, organism-specific biosystem
• Function: identical protein binding; motor activity; protein binding