Recombinant Human EGFR, Fc Chimera

• Cat.No.: EGFR-692H
• Product Overview: Recombinant human EGFR (NP_005219) extracellular domain (Met1-Gly640), fused with the Fc region of human IgG1 at the C-terminus, was produced in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: 1-640 a.a.
• Predicted N Terminal: Leu 25
• Form: Lyophilized from sterile PBS, pH7.4.
• Molecular Mass: The recombinant human EGFR/Fc chimera is a homodimeric protein. The reduced monomer consists of 860 amino acids and has a calculated molecular mass of 95 KDa. As a result of glycosylation, the recombinant protein migrates as an approximately 130-140 KDa p
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >97% as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70oC.
• Storage: Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.
• Publications:
  Nanofitin as a new molecular imaging agent for diagnosis of EGFR overexpressing tumors. (2017)

Gene Information

• Gene Name: EGFR epidermal growth factor receptor [ Homo sapiens ]
• Official Symbol: EGFR
• Gene ID: 1956
• mRNA Refseq: NM_005228
• Protein Refseq: NP_005219
• MIM: 131550
• UniProt ID: P00533
• Chromosome Location: 7p12