Recombinant Human EIF4G2 Protein, GST-tagged
Cat.No. : | EIF4G2-3211H |
Product Overview : | Human EIF4G2 partial ORF ( NP_001409, 811 a.a. - 889 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 34.43 kDa |
AA Sequence : | SFKPVMQKFLHDHVDLQVSALYALQ VHCYNSNFPKGMLLRFFVHFYDMEI IEEEAFLAWKEDITQEFPGKGKALF QVNQ |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 [ Homo sapiens ] |
Official Symbol : | EIF4G2 |
Synonyms : | EIF4G2; eukaryotic translation initiation factor 4 gamma, 2; eukaryotic translation initiation factor 4 gamma 2; DAP5; NAT1; p97; DAP-5; eIF4G 2; eIF-4G 2; eIF-4-gamma 2; aging-associated protein 1; death-associated protein 5; eukaryotic translation initiation factor 4G-like 1; P97; AAG1; FLJ41344; |
Gene ID : | 1982 |
mRNA Refseq : | NM_001042559 |
Protein Refseq : | NP_001036024 |
MIM : | 602325 |
UniProt ID : | P78344 |
Products Types
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EIF4G2-3725C | Recombinant Chicken EIF4G2 | +Inquiry |
◆ Lysates | ||
EIF4G2-6646HCL | Recombinant Human EIF4G2 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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