Recombinant Human EOMES Protein, Myc/DDK-tagged
Cat.No. : | EOMES-3345H |
Product Overview : | Recombinant protein of Human eomesodermin (EOMES), full length, with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. |
Source : | HEK293T |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 72.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris-HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Gene Name : | EOMES eomesodermin [ Homo sapiens (human) ] |
Official Symbol : | EOMES |
Synonyms : | EOMES; eomesodermin; TBR2; eomesodermin homolog; T-box brain protein 2 |
Gene ID : | 8320 |
mRNA Refseq : | NM_005442 |
Protein Refseq : | NP_005433 |
MIM : | 604615 |
UniProt ID : | O95936 |
Products Types
◆ Recombinant Protein | ||
EOMES-2807M | Recombinant Mouse EOMES Protein, His (Fc)-Avi-tagged | +Inquiry |
EOMES-3344H | Recombinant Human EOMES Protein, GST-tagged | +Inquiry |
EOMES-1649H | Recombinant Human EOMES protein, His & GST-tagged | +Inquiry |
EOMES-389H | Recombinant Human EOMES Protein, His-tagged | +Inquiry |
EOMES-5228M | Recombinant Mouse EOMES Protein | +Inquiry |
◆ Lysates | ||
EOMES-6589HCL | Recombinant Human EOMES 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Reviews
Q&As (6)
Ask a questionEOMES can affect the production, progression and prognosis of lung cancer by regulating CTLs function and immune surveillance cell types and functions.
EOMES plays a key role in the differentiation and function of CD8+ T cells, particularly in the formation and stability maintenance of effector memory T cells and cytotoxic T lymphocytes (CTLs).
The molecular mechanisms of EOMES genes can be studied by analyzing the association between the EOMES gene and immune-related diseases such as autoimmune diseases, infectious diseases, etc.
Yes, EOMES is strongly associated with the occurrence and progression of a variety of lymphoid tumors (such as Hodgkin lymphoma, T-cell lymphoma, etc.).
Mouse gene knockout technology, small RNA interference technology, etc. can be used to study the role of EOMES in the immune system.
EOMES can enhance the reactivity of T lymphocytes in tumor immunotherapy, thereby enhancing the killing ability and therapeutic effect of tumor cells.
Customer Reviews (3)
Write a reviewThe storage conditions and experimental environment of this protein are simple and convenient without specific conditions.
Less polluting and minimizes waste.
You can see that this protein is produced with great care for purity and activity.
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