Recombinant Human FGF1, His-tagged
Cat.No. : | FGF1-26555TH |
Product Overview : | Recombinant full length human FGF1 with His tag expressed in a baculovirus system; amino acids 16-155 , approximately 18kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. |
Conjugation : | HIS |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the heparin-binding growth factors family. |
Gene Name : | FGF1 fibroblast growth factor 1 (acidic) [ Homo sapiens ] |
Official Symbol : | FGF1 |
Synonyms : | FGF1; fibroblast growth factor 1 (acidic); FGFA; heparin-binding growth factor 1; AFGF; ECGF; ECGF beta; ECGFA; ECGFB; endothelial cell growth factor; alpha; beta; FGF alpha; GLIO703; HBGF1; heparin binding growth factor 1; |
Gene ID : | 2246 |
mRNA Refseq : | NM_000800 |
Protein Refseq : | NP_000791 |
MIM : | 131220 |
Uniprot ID : | P05230 |
Chromosome Location : | 5q31.3-q33.2 |
Pathway : | Downstream signaling of activated FGFR, organism-specific biosystem; FGF signaling pathway, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR1 ligand binding and activation, organism-specific biosystem; FGFR1b ligand binding and activation, organism-specific biosystem; |
Function : | S100 alpha binding; fibroblast growth factor receptor binding; growth factor activity; heparin binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
FGF1-038H | Recombinant Human FGF1 Protein | +Inquiry |
FGF1-928C | Recombinant Cattle FGF1 Protein, His-tagged | +Inquiry |
FGF1-10H | Active Recombinant Human FGF1 Protein (Carry Free-Ready-To-Use, 140 amino acid) | +Inquiry |
FGF1-81H | Recombinant Human FGF1 Protein | +Inquiry |
FGF1-043H | Active Recombinant Human FGF1 Protein | +Inquiry |
◆ Native Protein | ||
FGF1-33B | Active Native Bovine FGF1 | +Inquiry |
FGF1-26203TH | Native Human FGF1 | +Inquiry |
◆ Lysates | ||
FGF1-6252HCL | Recombinant Human FGF1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (5)
Ask a questionYes, there have been clinical trials exploring the use of FGF1 in treating heart disease, specifically in promoting cardiac angiogenesis.
Yes, FGF1 is being investigated for its potential in regenerative medicine to repair damaged tissues and organs.
FGF1 has shown potential in improving insulin sensitivity and glucose regulation in preclinical studies, but further research is needed for clinical applications.
Safety concerns include the risk of uncontrolled cell growth, which could lead to cancer, and the need for precise dosing and administration.
Potential side effects may include inflammation at the application site, allergic reactions, and adverse effects related to uncontrolled cell growth.
Customer Reviews (3)
Write a reviewBy using FGF1 protein, I can explore the mechanisms underlying cell division, cell cycle control, and the molecular pathways associated with these processes.
The protein's interaction with other APC/C subunits enables the study of its function and the investigation of its involvement in various cellular processes.
As a researcher utilizing FGF1 protein in my trials, I can highlight its advantages and the valuable support provided by the manufacturer in facilitating my research.
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