Recombinant Human FLT1 Protein

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Recombinant Human FLT1 Protein

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Cat.No. : FLT1-4366H
Product Overview : Human FLT1 (NP_002010.1, 31 a.a. - 328 a.a.) partial recombinant protein expressed in Escherichia coli.
Description : This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia
Source : E. coli
Species : Human
Form : Liquid
AA Sequence : SLKGTQHIMQAGQTL HLQCRGEAAHKWSLP EMVSKESERLSITKS ACGRNGKQFCSTLTL NTAQANHTGFYSCKY LAVPTSKKKETESAI YIFISDTGRPFVEMY SEIPEIIHMTEGREL VIPCRVTSPNITVTL KKFPLDTLIPDGKRI IWDSRKGFIISNATY KEIGLLTCEATVNGH LYKTNYLTHRQTNTI IDVQISTPRPVKLLR GHTLVLNCTATTPLN TRVQMTWSYPDEKNK RASVRRRIDQSNSHA NIFYSVLTIDKMQNK DKGLYTCRVRSGPSF KSVNTSVHI
Purity : > 95% by SDS-PAGE
Applications : Western Blot
Immunohistochemistry
ELISA
Dot Blot
SDS-PAGE
Storage : Store at -20 centigrade. For long term storage store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : In Tris (50% glycerol)
Quality Control Testing :

10% SDS-PAGE Result

Gene Name : FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) [ Homo sapiens ]
Official Symbol : FLT1
Synonyms : FLT1; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor); FLT; vascular endothelial growth factor receptor 1; VEGFR1; FLT-1; VEGFR-1; fms-like tyrosine kinase 1; tyrosine-protein kinase FRT; tyrosine-protein kinase receptor FLT; vascular permeability factor receptor;
Gene ID : 2321
mRNA Refseq : NM_001159920
Protein Refseq : NP_001153392
MIM : 165070
UniProt ID : P17948

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