Recombinant Human Fms-Related Tyrosine Kinase 3
Cat.No. : | FLT3-1225H |
Product Overview : | Recombinant humanFLT3 is Expressed in HEK 293 cells. |
- Specification
- Gene Information
- Related Products
Cat. No. : | FLT3-1225H |
Description : | FLT3 Ligand is expressed from human 293cells as a monomeric glycoprotein with an apparent MW 24 to 30 kDa. Thiscytokine is produced in a serum-free, chemically defined media. The molecularmass is a narrower range than reported when this cytokine is expressed ininsect Sf21 cells (17 to 30 kDa), emphasizing the difference in glycosylationin different expression systems. |
Source : | HEK 293 cells |
Species : | Human |
MolecularWeight : | 24 to 30 kDamonomer, glycosylated |
Purity : | > 95% The proteinwas resolved by SDS polyacrylamide gel electrophoresis and the gel wasstained with Coomassie blue. |
Endotoxin Level : | Endotoxin Free <1EU/ug |
Biological Activity : | 0.2 to 0.8 ng/mLED50 |
Storage : | The specificactivity was determined by the dose-dependent stimulation of theproliferation of the human acute myeloid leukemia cell line OCI-AML5. |
Gene Name : | FLT3 fms-related tyrosine kinase 3 [ Homosapiens ] |
Official Symbol : | FLT3 |
Synonyms : | FLT3; fms-related tyrosinekinase 3; FLK2; STK1; CD135; CD135 antigen; fetal liver kinase 2; FL cytokinereceptor; tal liver kinase 2; stem cell tyrosine kinase 1; FLT3 receptortyrosine kinase; tyrosine-protein kinase receptor FLT3; growth factorreceptor tyrosine kinase type III; C 2.7.10.1; OTTHUMP00000042340; fetalliver kinase 2 |
Gene ID : | 2322 |
mRNA Refseq : | NM_004119 |
Protein Refseq : | NP_004110 |
MIM : | 136351 |
UniProt ID : | P36888 |
Chromosome Location : | 13q12 |
Pathway : | Acute myeloidleukemia; Cytokine-cytokine receptor interaction; Hematopoietic cell lineage;Pathways in cancer |
Function : | ATP binding; nucleotidebinding; osphoinositide 3-kinase binding; protein binding; receptor activity;transferase activity; vascular endothelial growth factor receptor activity |
Products Types
◆ Recombinant Protein | ||
FLT3-038H | Recombinant Human FLT3 Protein, C-His-tagged | +Inquiry |
FLT3-1155R | Recombinant Rhesus Monkey FLT3 Protein, His-tagged | +Inquiry |
FLT3-97P | Active Recombinant Porcine FLT-3 Ligand Protein | +Inquiry |
FLT3-188H | Recombinant Human FLT3 Protein, His (Fc)-Avi-tagged | +Inquiry |
FLT3-4370H | Active Recombinant Human FLT3 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
FLT3-2561HCL | Recombinant Human FLT3 cell lysate | +Inquiry |
FLT3-970MCL | Recombinant Mouse FLT3 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1593 | Flt3 Activity Assay Kit | +Inquiry |
Kit-1592 | Flt3 ActivityAssay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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