| Description : |
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
59.3 kDa |
| AA Sequence : |
MAEQVALSRTQVCGILREELFQGDA FHQSDTHIFIIMGASGDLAKKKIYP TIWWLFRDGLLPENTFIVGYARSRL TVADIRKQSEPFFKATPEEKLKLED FFARNSYVAGQYDDAASYQRLNSHM NALHLGSQANRLFYLALPPTVYEAV TKNIHESCMSQIGWNRIIVEKPFGR DLQSSDRLSNHISSLFREDQIYRID HYLGKEMVQNLMVLRFANRIFGPIW NRDNIACVILTFKEPFGTEGRGGYF DEFGIIRDVMQNHLLQMLCLVAMEK PASTNSDDVRDEKVKVLKCISEVQA NNVVLGQYVGNPDGEGEATKGYLDD PTVPRGSTTATFAAVVLYVENERWD GVPFILRCGKALNERKAEVRLQFHD VAGDIFHQQCKRNELVIRVQPNEAV YTKMMTKKPGMFFNPEESELDLTYG NRYKNVKLPDAYERLILDVFCGSQM HFVRSDELREAWRIFTPLLHQIELE KPKPIPYIYGSRGPTEADELMKRVG FQYEGTYKWVNPHKLTRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
