| Species : |
Human |
| Source : |
Insect Cells |
| Tag : |
Flag |
| Protein Length : |
M1-F758 end, L573F |
| Description : |
This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants. |
| Form : |
Liquid |
| Endotoxin : |
< 0.01 EU/μg of the protein |
| Purity : |
90% |
| Stability : |
Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade |
| Storage : |
Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Storage Buffer : |
Supplied as sterile 150 mM NaCl, 20 mM HEPES (pH 7.5), 10 mM DTT, 10 mM CaCl2, 0.005% GDN |
| Shipping : |
It is shipped out with blue ice. |
