Recombinant Human GLRX2, GST-tagged

• Cat.No.: GLRX2-13312H
• Product Overview: Recombinant Human GLRX2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 16-164a.a.
• Description: The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GLRX2 glutaredoxin 2 [ Homo sapiens ]
• Official Symbol: GLRX2
• Synonyms: GLRX2; glutaredoxin 2; bA101E13.1; bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2); GRX2; CGI-133
• Gene ID: 51022
• mRNA Refseq: NM_001243399
• Protein Refseq: NP_001230328
• MIM: 606820
• UniProt ID: Q9NS18
• Chromosome Location: 1p31.2-q31.3
• Function: 2 iron, 2 sulfur cluster binding; arsenate reductase (glutaredoxin) activity; electron carrier activity; glutathione disulfide oxidoreductase activity; metal ion binding; protein disulfide oxidoreductase activity