Recombinant Human GRB10 Protein, Myc/DDK-tagged, C13 and N15-labeled GRB10-5227H

Recombinant Human GRB10 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : GRB10-5227H Optional Service: Optional requirements on this protein
Product Overview : GRB10 MS Standard C13 and N15-labeled recombinant protein (NP_001001555) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 60.8 kDa
AA Sequence : MNASLESLYS ACSMQSDTVP LLQNGQHARS QPRASGPPRS IQPQVSPRQR VQRSQPVHIL AVRRLQEEDQ QFRTSSLPAI PNPFPELCGP GSPPVLTPGS LPPSQAAAKQ DVKVFSEDGT SKVVEILADM TARDLCQLLV YKSHCVDDNS WTLVEHHPHL GLERCLEDHE LVVQVESTMA SESKFLFRKN YAKYEFFKNP MNFFPEQMVT WCQQSNGSQT QLLQNFLNSS SCPEIQGFLH VKELGKKSWK KLYVCLRRSG LYCSTKGTSK EPRHLQLLAD LEDSNIFSLI AGRKQYNAPT DHGLCIKPNK VRNETKELRL LCAEDEQTRT CWMTAFRLLK YGMLLYQNYR IPQQRKALLS PFSTPVRSVS ENSLVAMDFS GQTGRVIENP AEAQSAALEE GHAWRKRSTR MNILGSQSPL HPSTLSTVIH RTQHWFHGRI SREESHRIIK QQGLVDGLFL LRDSQSNPKA FVLTLCHHQK IKNFQILPCE DDGQTFFSLD DGNTKFSDLI QLVDFYQLNK GVLPCKLKHH CIRVALSGPT RTRPLEQKLI SEEDLAANDI LDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : GRB10 growth factor receptor-bound protein 10 [ Homo sapiens (human) ]
Official Symbol : GRB10
Synonyms : GRB10; growth factor receptor-bound protein 10; GRB10 adapter protein; GRB10 adaptor protein; maternally expressed gene 1; insulin receptor-binding protein Grb-IR; RSS; IRBP; MEG1; GRB-IR; Grb-10; KIAA0207;
Gene ID : 2887
mRNA Refseq : NM_001001555
Protein Refseq : NP_001001555
MIM : 601523
UniProt ID : Q13322
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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