Recombinant Human GRN Protein, GST-tagged
Cat.No. : | GRN-5375H |
Product Overview : | Human GRN full-length ORF ( NP_002078.1, 1 a.a. - 593 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 89.9 kDa |
AA Sequence : | MWTLVSWVALTAGLVAGTRCPDGQF CPVACCLDPGGASYSCCRPLLDKWP TTLSRHLGGPCQVDAHCSAGHSCIF TVSGTSSCCPFPEAVACGDGHHCCP RGFHCSADGRSCFQRSGNNSVGAIQ CPDSQFECPDFSTCCVMVDGSWGCC PMPQASCCEDRVHCCPHGAFCDLVH TRCITPTGTHPLAKKLPAQRTNRAV ALSSSVMCPDARSRCPDGSTCCELP SGKYGCCPMPNATCCSDHLHCCPQD TVCDLIQSKCLSKENATTDLLTKLP AHTVGDVKCDMEVSCPDGYTCCRLQ SGAWGCCPFTQAVCCEDHIHCCPAG FTCDTQKGTCEQGPHQVPWMEKAPA HLSLPDPQALKRDVPCDNVSSCPSS DTCCQLTSGEWGCCPIPEAVCCSDH QHCCPQGYTCVAEGQCQRGSEIVAG LEKMPARRASLSHPRDIGCDQHTSC PVGQTCCPSLGGSWACCQLPHAVCC EDRQHCCPAGYTCNVKARSCEKEVV SAQPATFLARSPHVGVKDVECGEGH FCHDNQTCCRDNRQGWACCPYRQGV CCADRRHCCPAGFRCAARGTKCLRR EAPRWDAPLRDPALRQLL |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | GRN granulin [ Homo sapiens ] |
Official Symbol : | GRN |
Synonyms : | GRN; granulin; granulins; CLN11; PCDGF; PGRN; progranulin; acrogranin; proepithelin; granulin-epithelin; PC cell-derived growth factor; GEP; GP88; PEPI; |
Gene ID : | 2896 |
mRNA Refseq : | NM_002087 |
Protein Refseq : | NP_002078 |
MIM : | 138945 |
UniProt ID : | P28799 |
Products Types
◆ Recombinant Protein | ||
Grn-1593R | Recombinant Rat Grn Protein, His-tagged | +Inquiry |
Grn-1065M | Recombinant Mouse Grn Protein, MYC/DDK-tagged | +Inquiry |
GRN-1022H | Recombinant Human GRN Protein, His (Fc)-Avi-tagged | +Inquiry |
GRN-2358H | Recombinant Human GRN Protein, MYC/DDK-tagged | +Inquiry |
GRN-2709H | Recombinant Human GRN protein(491-570 aa), C-His-tagged | +Inquiry |
◆ Lysates | ||
GRN-2412MCL | Recombinant Mouse GRN cell lysate | +Inquiry |
GRN-2791HCL | Recombinant Human GRN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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