Recombinant Human GSK3B Protein, MYC/DDK-tagged, C13 and N15-labeled

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Recombinant Human GSK3B Protein, MYC/DDK-tagged, C13 and N15-labeled

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Cat.No. : GSK3B-012H
Product Overview : GSK3B MS Standard C13 and N15-labeled recombinant protein (NP_002084) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 47.9 kDa
AA Sequence : MSGRPRTTSF AESCKPVQQP SAFGSMKVSR DKDGSKVTTV VATPGQGPDR PQEVSYTDTK VIGNGSFGVV YQAKLCDSGE LVAIKKVLQD KRFKNRELQI MRKLDHCNIV RLRYFFYSSG EKKDEVYLNL VLDYVPETVY RVARHYSRAK QTLPVIYVKL YMYQLFRSLA YIHSFGICHR DIKPQNLLLD PDTAVLKLCD FGSAKQLVRG EPNVSYICSR YYRAPELIFG ATDYTSSIDV WSAGCVLAEL LLGQPIFPGD SGVDQLVEII KVLGTPTREQ IREMNPNYTE FKFPQIKAHP WTKDSSGTGH FTSGVRVFRP RTPPEAIALC SRLLEYTPTA RLTPLEACAH SFFDELRDPN VKLPNGRDTP ALFNFTTQEL SSNPPLATIL IPPHARIQAA ASTPTNATAA SDANTGDRGQ TNNAASASAS NSTTRTRPLE QKLISEEDLA ANDILDYKDD DDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : GSK3B glycogen synthase kinase 3 beta [ Homo sapiens (human) ]
Official Symbol : GSK3B
Synonyms : GSK3B; glycogen synthase kinase 3 beta; glycogen synthase kinase-3 beta; glycogen synthase kinase 3 beta; GSK3beta isoform; glycogen synthase kinase-3 beta; GSK-3 beta; serine/threonine-protein kinase GSK3B; EC 2.7.11.1; EC 2.7.11.26
Gene ID : 2932
mRNA Refseq : NM_002093
Protein Refseq : NP_002084
MIM : 605004
UniProt ID : P49841
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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