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Active Recombinant Human GUSB Protein

Cat.No. : GUSB-001H
Product Overview : Recombinant human GUSB protein containing 635 amino acids (23-651a.a) fused to a 6 amino acid His-tag at C-terminus was produced in Sf9 Baculovirus cells.
  • Specification
  • Gene Information
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Description : This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII.
Source : Insect cell
Species : Human
Tag : His
Form : Sterile Filtered colorless solution
Bio-activity : Specific activity is > 1600 pmol/min/ug and is defined as the amount of enzyme that hydrolyze 1.0 pmole of 4-Methylumbelliferone to 4- Methylum-belliferyl-β-D-glucosiduronic acid per minute at 37 centigrade and pH6.0.
Molecular Mass : 73.4 kDa
AA Sequence : LQGGMLYPQESPSRECKELDGLWSF RADFSDNRRRGFEEQWYRRPLWESG PTVDMPVPSSFNDISQDWRLRHFVG WVWYEREVILPERWTQDLRTRVVLR IGSAHSYAIVWVNGVDTLEHEGGYL PFEADISNLVQVGPLPSRLRITIAI NNTLTPTTLPPGTIQYLTDTSKYPK GYFVQNTYFDFFNYAGLQRSVLLYT TPTTYIDDITVTTSVEQDSGLVNYQ ISVKGSNLFKLEVRLLDAENKVVAN GTGTQGQLKVPGVSLWWPYLMHERP AYLYSLEVQLTAQTSLGPVSDFYTL PVGIRTVAVTKSQFLINGKPFYFHG VNKHEDADIRGKGFDWPLLVKDFNL LRWLGANAFRTSHYPYAEEVMQMCD RYGIVVIDECPGVGLALPQFFNNVS LHHHMQVMEEVVRRDKNHPAVVMWS VANEPASHLESAGYYLKMVIAHTKS LDPSRPVTFVSNSNYAADKGAPYVD VICLNSYYSWYHDYGHLELIQLQLA TQFENWYKKYQKPIIQSEYGAETIA GFHQDPPLMFTEEYQKSLLEQYHLG LDQKRRKYVVGELIWNFADFMTEQS PTRVLGNKKGIFTRQRQPKSAAFLL RERYWKIANETRYPHSVAKSQCLEN SLFTHHHHHH
Purity : Greater than 90.0% as determined by SDS-PAGE.
Usage : This products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Storage : Store at 4 centigrade if entire vial will be used within 2-4 weeks. Store, frozen at -20 centigrade for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Storage Buffer : GUSB protein solution (0.25 mg/ml) containing Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Gene Name : GUSB glucuronidase beta [ Homo sapiens (human) ]
Official Symbol : GUSB
Synonyms : GUSB; glucuronidase beta; BG; MPS7; beta-glucuronidase; beta-D-glucuronidase; beta-G1; EC 3.2.1.31
Gene ID : 2990
mRNA Refseq : NM_000181
Protein Refseq : NP_000172
MIM : 611499
UniProt ID : P08236

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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