Recombinant Human HBB Mutant (T87Q) Protein, Myc/DDK-tagged
Cat.No. : | HBB-059H |
Product Overview : | Purified mutant recombinant protein of Human hemoglobin, beta (HBB), mutation at(T87Q) with a Myc/DDK tag was expressed in HEK293 |
- Specification
- Gene Information
- Related Products
Description : | The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 15.8 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for at least 12 months from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | > 50 μg/mL as determined by microplate Bradford method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Gene Name : | HBB hemoglobin subunit beta [ Homo sapiens (human) ] |
Official Symbol : | HBB |
Synonyms : | HBB; hemoglobin subunit beta; ECYT6; CD113t-C; beta-globin; hemoglobin subunit beta; beta globin chain; hemoglobin beta subunit; hemoglobin, beta |
Gene ID : | 3043 |
mRNA Refseq : | NM_000518 |
Protein Refseq : | NP_000509 |
MIM : | 141900 |
UniProt ID : | P68871 |
Products Types
◆ Native Protein | ||
HBB-001H | Native Human Hemoglobin S, Ferrous Stabilized | +Inquiry |
HBb-49S | Native Sheep Hemoglobin Beta (HBb) Protein | +Inquiry |
◆ Lysates | ||
HBB-5622HCL | Recombinant Human HBB 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionHBB, part of the hemoglobin molecule, is crucial for oxygen transport in the blood.
Therapies targeting HBB mutations aim to correct or compensate for the defective hemoglobin in blood disorders.
HBB mutations can lead to abnormal hemoglobin, resulting in impaired oxygen transport and cell damage.
It forms part of hemoglobin's structure, binding oxygen in red blood cells.
Altered HBB expression affects hemoglobin's efficiency, impacting oxygen delivery and health.
HBB interacts with other hemoglobin subunits to form a functional oxygen-carrying complex.
Mutations in HBB cause sickle cell anemia and thalassemia, affecting hemoglobin's function.
Customer Reviews (3)
Write a reviewHelps us reach milestones. Efficient and accurate service.
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