Recombinant Human HLA-DMB Protein, MYC/DDK-tagged
Cat.No. : | HLA-DMB-324H |
Product Overview : | Recombinant Human HLA-DMB fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 27.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | HLA-DMB major histocompatibility complex, class II, DM beta [ Homo sapiens ] |
Official Symbol : | HLA-DMB |
Synonyms : | HLA-DMB; major histocompatibility complex, class II, DM beta; HLA class II histocompatibility antigen, DM beta chain; D6S221E; RING7; MHC class II HLA-DMB; MHC class II antigen DMB; really interesting new gene 7 protein; MHC class II antigen HLA-DM beta chain; class II histocompatibility antigen, M beta chain; |
Gene ID : | 3109 |
mRNA Refseq : | NM_002118 |
Protein Refseq : | NP_002109 |
MIM : | 142856 |
UniProt ID : | P28068 |
Products Types
◆ Recombinant Protein | ||
HLA-DMB-4837H | Recombinant Human HLA-DMB Protein, GST-tagged | +Inquiry |
HLA-DMB-3989H | Recombinant Human HLA-DMB protein, His-tagged | +Inquiry |
HLA-DMB-13813H | Recombinant Human HLA-DMB, GST-tagged | +Inquiry |
◆ Lysates | ||
HLA-DMB-5500HCL | Recombinant Human HLA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket