Recombinant Human HLA-DPA1 Protein, GST-tagged

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Recombinant Human HLA-DPA1 Protein, GST-tagged

HLA-DPA1 Related Products

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Cat.No. : HLA-DPA1-4840H
Product Overview : Human HLA-DPA1 full-length ORF ( AAH09956, 1 a.a. - 260 a.a.) recombinant protein with GST-tag at N-terminal.
Description : HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 54.34 kDa
AA Sequence : MRPEDRMFHI RAVILRALSL AFLLSLRGAG AIKADHVSTY AAFVQTHRPT GEFMFEFDED EQFYVDLDKK ETVWHLEEFG RAFSFEAQGG LANIAILNNN LNTLIQRSNH TQAANDPPEV TVFPKEPVEL GQPNTLICHI DRFFPPVLNV TWLCNGEPVT EGVAESLFLP RTDYSFHKFH YLTFVPSAED VYDCRVEHWG LDQPLLKHWE AQEPIQMPET TETVLCALGL VLGLVGIIVG TVLIIKSLRS GHDPRAQGPL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 [ Homo sapiens ]
Official Symbol : HLA-DPA1
Synonyms : HLA-DPA1; major histocompatibility complex, class II, DP alpha 1; HLA DP1A; HLA class II histocompatibility antigen, DP alpha 1 chain; MHC class II DPA1; HLA-SB alpha chain; MHC class II antigen; MHC class II DP3-alpha; Primed lymphocyte test-1; MHC class II HLA-DPA1 antigen; HLA class II histocompatibility antigen, DP alpha chain; PLT1; HLADP; HLASB; DP(W3); DP(W4); HLA-DP1A;
Gene ID : 3113
mRNA Refseq : NM_001242524
Protein Refseq : NP_001229453
MIM : 142880
UniProt ID : P20036

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