Recombinant Human HTR5A Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: HTR5A-2295H
• Product Overview: HTR5A MS Standard C13 and N15-labeled recombinant protein (NP_076917) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 40.3 kDa
• AA Sequence: MDLPVNLTSFSLSTPSPLETNHSLG KDDLRPSSPLLSVFGVLILTLLGFL VAATFAWNLLVLATILRVRTFHRVP HNLVASMAVSDVLVAALVMPLSLVH ELSGRRWQLGRRLCQLWIACDVLCC TASIWNVTAIALDRYWSITRHMEYT LRTRKCVSNVMIALTWALSAVISLA PLLFGWGETYSEGSEECQVSREPSY AVFSTVGAFYLPLCVVLFVYWKIYK AAKFRVGSRKTNSVSPISEAVEVKD SAKQPQMVFTVRHATVTFQPEGDTW REQKEQRAALMVGILIGVFVLCWIP FFLTELISPLCSCDIPAIWKSIFLW LGYSNSFFNPLIYTAFNKNYNSAFK NFFSRQHTRTRPLEQKLISEEDLAA NDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: HTR5A 5-hydroxytryptamine receptor 5A [ Homo sapiens (human) ]
• Official Symbol: HTR5A
• Synonyms: HTR5A; 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled; 5 hydroxytryptamine (serotonin) receptor 5A; 5-hydroxytryptamine receptor 5A; 5 HT5A; 5-HT-5; 5-HT-5A; serotonin receptor 5A; 5-HT5A; MGC138226
• Gene ID: 3361
• mRNA Refseq: NM_024012
• Protein Refseq: NP_076917
• MIM: 601305
• UniProt ID: P47898