Recombinant Human IKBKB protein, His & GST-tagged

• Cat.No.: IKBKB-1720H
• Product Overview: Recombinant Human IKBKB aa. (Asp246~Val528 (Accession # O14920)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: Asp246~Val528
• Description: The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 62.3kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >90%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Reconstitution: Reconstitute in sterile ddH2O.
• Isoelectric Point: 5.4

Gene Information

• Gene Name: IKBKB inhibitor of nuclear factor kappa B kinase subunit beta [ Homo sapiens (human) ]
• Official Symbol: IKBKB
• Synonyms: IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta; IKK2; IKKB; IMD15; NFKBIKB; IKK-beta; inhibitor of nuclear factor kappa-B kinase subunit beta; I-kappa-B kinase 2; I-kappa-B-kinase beta; IKK-B; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; nuclear factor NF-kappa-B inhibitor kinase beta
• Gene ID: 3551
• mRNA Refseq: NM_001190720.2
• Protein Refseq: NP_001177649.1
• UniProt ID: O14920