Recombinant Human IL10RB protein, His-tagged

• Cat.No.: IL10RB-581H

Specification

• Product overview: Recombinant Human IL10RB (Q08334) aa. (Leu87~Ala243) fused with His tag was produced in E. coli cells.
• Description: The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 19.5kDa; Accurate Molecular Mass: 18kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Leu87~Ala243
• Purity: >98%
• Characteristic: Isoelectric point is 5.
• Applications: Cell culture; Activity Assays; In vivo assays.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: 20mM Tris, 150mM NaCl,pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex

Gene Information

• Gene Name: IL10RB interleukin 10 receptor subunit beta [ Homo sapiens (human) ]
• Official Symbol: IL10RB
• Synonyms: IL10RB; interleukin 10 receptor subunit beta; CRFB4; CRF2-4; D21S58; D21S66; CDW210B; IL-10R2; interleukin-10 receptor subunit beta; IL-10 receptor subunit beta; IL-10R subunit 2; IL-10R subunit beta; IL-10RB; cytokine receptor class-II CRF2-4; cytokine receptor class-II member 4; cytokine receptor family 2 member 4; cytokine receptor family II, member 4; interleukin 10 receptor, beta; interleukin-10 receptor subunit 2
• Gene ID: 3588
• mRNA Refseq: NM_000628.4
• Protein Refseq: NP_000619.3
• UniProt ID: Q08334