"IL13" Related Products


Recombinant Human IL13 Protein, His-tagged

Cat.No. : IL13-3589H
Product Overview : Recombinant human IL-13 protein (Gly 21 - Asn 132) with His tag is expressed from human 293 cells (HEK293).
Description : This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.
Source : HEK293
Species : Human
Tag : His
Molecular Mass : 14.2 kDa
N-terminal Sequence Analysis : Gly 21
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >90% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
No activity loss was observed after storage at:
4-8 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Storage Buffer : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Gene Name : IL13 interleukin 13 [ Homo sapiens (human) ]
Official Symbol : IL13
Synonyms : IL13; interleukin 13; P600; IL-13; interleukin-13; ALRH; BHR1; MGC116786; MGC116788; MGC116789; P600; Interleukin-13
Gene ID : 3596
mRNA Refseq : NM_002188
Protein Refseq : NP_002179
MIM : 147683
UniProt ID : P35225

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