| Description : |
This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
82.2 kDa |
| AA Sequence : |
MAPWLQLCSVFFTVNACLNGSQLAV AAGGSGRARGADTCGWRGVGPASRN SGLYNITFKYDNCTTYLNPVGKHVI ADAQNITISQYACHDQVAVTILWSP GALGIEFLKGFRVILEELKSEGRQC QQLILKDPKQLNSSFKRTGMESQPF LNMKFETDYFVKVVPFPSIKNESNY HPFFFRTRACDLLLQPDNLACKPFW KPRNLNISQHGSDMQVSFDHAPHNF GFRFFYLHYKLKHEGPFKRKTCKQE QTTETTSCLLQNVSPGDYIIELVDD TNTTRKVMHYALKPVHSPWAGPIRA VAITVPLVVISAFATLFTVMCRKKQ QENIYSHLDEESSESSTYTAALPRE RLRPRPKVFLCYSSKDGQNHMNVVQ CFAYFLQDFCGCEVALDLWEDFSLC REGQREWVIQKIHESQFIIVVCSKG MKYFVDKKNYKHKGGGRGSGKGELF LVAVSAIAEKLRQAKQSSSAALSKF IAVYFDYSCEGDVPGILDLSTKYRL MDNLPQLCSHLHSRDHGLQEPGQHT RQGSRRNYFRSKSGRSLYVAICNMH QFIDEEPDWFEKQFVPFHPPPLRYR EPVLEKFDSGLVLNDVMCKPGPESD FCLKVEAAVLGATGPADSQHESQHG GLDQDGEARPALDGSAALQPLLHTV KAGSPSDMPRDSGIYDSSVPSSELS LPLMEGLSTDQTETSSLTESVSSSS GLGEEEPPALPSKLLSSGSCKADLG CRSYTDELHAVAPLTRTRPLEQKLI SEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
