Recombinant Human IL18 Protein, His-tagged
Cat.No. : | IL18-94H |
Product Overview : | Recombinant Human Interleukin-18 is produced by our Mammalian expression system and the target gene encoding Tyr37-Asp193 is expressed with a 6His tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-γ (IFN-γ) or type II interferon that plays an important role in activating the macrophages or other cells. |
Source : | Human Cells |
Species : | Human |
Tag : | His |
Form : | Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. |
Molecular Mass : | Predicted Molecular Weight: 19.25kDa Apparent Molecular Weight: 23kDa, reducing conditions. |
AA Sequence : | Tyr37-Asp193 |
Endotoxin : | Less than 0.1 ng/ug (1 EU/ug). |
Purity : | >90% |
Storage : | Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days. Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months. |
Reconstitution : | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Quality Statement : | Purity: Greater than 90% as determined by reducing SDS-PAGE. |
Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Gene Name : | IL18 interleukin 18 [ Homo sapiens (human) ] |
Official Symbol : | IL18 |
Synonyms : | Interleukin-18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma; GIF; IL-18; IL-1g; IL1F4; MGC12320; IGIF |
Gene ID : | 3606 |
mRNA Refseq : | NM_001243211.2 |
Protein Refseq : | NP_001230140.1 |
MIM : | 600953 |
UniProt ID : | Q14116 |
Products Types
◆ Recombinant Protein | ||
Il18-1241M | Recombinant Mouse Il18 Protein, MYC/DDK-tagged | +Inquiry |
Il18-155M | Recombinant Active Mouse IL18 Protein, His-tagged(C-ter) | +Inquiry |
IL18-2297H | Recombinant Human IL18 Protein, His-tagged | +Inquiry |
IL18-1010G | Recombinant Goat IL18 Protein, His-tagged | +Inquiry |
IL18-183H | Active Recombinant Human IL18 Protein (Tyr37-Asp193), Animal-free, Carrier-free | +Inquiry |
◆ Lysates | ||
IL18-344HCL | Recombinant Human IL18 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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