Active Recombinant Human IL1R2 protein, His-tagged
Cat.No. : | IL1R2-2200H |
Product Overview : | Recombinant Human IL1R2 (Met 1-Glu 343) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from sterile 50 mM Tris, pH 8.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | Measured by its ability to inhibit Interferon gamma secretion by human natural killer lymphoma NK-92 cells in the presence of 500pg/mL IL1b. The EC50 for this effect is typically 20-80ng/mL. |
Molecular Mass : | The recombinant human IL1R2 consists of 341 amino acids and has a predicted molecular mass of 39.2 kDa. As a result of glycosylation, the rh IL1R2 migrates as an approximately 50-55 kDa band in SDS-PAGE under reducing conditions. |
Protein Length : | Met 1-Glu 343 |
Endotoxin : | < 1.0 EU per μg protein as determined by the LAL method. |
Purity : | > 95 % as determined by SDS-PAGE. > 90 % as determined by SEC-HPLC. |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | IL1R2 interleukin 1 receptor, type II [ Homo sapiens ] |
Official Symbol : | IL1R2 |
Synonyms : | IL1R2; interleukin 1 receptor, type II; IL1RB; interleukin-1 receptor type 2; CD121b; CDw121b; IL-1R-2; IL-1RT2; IL-1RT-2; IL-1R-beta; antigen CDw121b; IL-1 type II receptor; interleukin-1 receptor beta; interleukin-1 receptor type II; CD121 antigen-like family member B; type II interleukin-1 receptor, beta; MGC47725; |
Gene ID : | 7850 |
mRNA Refseq : | NM_004633 |
Protein Refseq : | NP_004624 |
MIM : | 147811 |
UniProt ID : | P27930 |
Products Types
◆ Recombinant Protein | ||
IL1R2-1821H | Recombinant Human IL1R2 Protein, MYC/DDK-tagged | +Inquiry |
IL1R2-165H | Recombinant Human IL1R2 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
Il1r2-1242M | Recombinant Mouse Il1r2 Protein, MYC/DDK-tagged | +Inquiry |
IL1R2-307H | Recombinant Human IL1R2 Protein, Fc-tagged | +Inquiry |
Il1r2-8700M | Active Recombinant Mouse Il1r2 protein(Met1-Glu355), His-tagged | +Inquiry |
◆ Lysates | ||
IL1R2-1227CCL | Recombinant Cynomolgus IL1R2 cell lysate | +Inquiry |
IL1R2-1376MCL | Recombinant Mouse IL1R2 cell lysate | +Inquiry |
IL1R2-1108HCL | Recombinant Human IL1R2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (10)
Ask a questionThe intracellular domain of IL1R2 has functional significance; engineered constructs clarify its role.
Glycosylation of IL1R2 affects its IL-1 ligand interaction, and glycoproteomics methods can reveal critical glycosylation sites.
Engineered IL1R2 variants offer insights into its mechanisms and therapeutic potential.
IL1R2's presence impacts IL-1 ligand signaling through competition with IL1R1; genetic manipulations unveil this interaction.
Post-translational modifications, including ubiquitination, influence IL1R2's stability.
IL1R2 expression responds to inflammation; transcription factors play a role in its regulation.
Super-resolution microscopy helps understand IL1R2's trafficking and subcellular dynamics in detail.
Specific structural elements of IL1R2 contribute to its decoy role; X-ray crystallography provides insights into ligand binding.
Ectodomain shedding contributes to IL1R2's soluble decoy role; specific enzymes are involved.
IL1R2's interaction with accessory proteins is significant for its decoy function.
Customer Reviews (3)
Write a reviewHigh specificity.
Good for flow cytometry.
Suitable for co-immunoprecipitation.
Ask a Question for All IL1R2 Products
Required fields are marked with *
My Review for All IL1R2 Products
Required fields are marked with *
Inquiry Basket