Recombinant Human IL1RAP Protein, MYC/DDK-tagged

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Cat.No. :	IL1RAP-1820H
Product Overview :	Recombinant human IL1RAP protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293
Description :	Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Nov 2009].
Source :	HEK293
Species :	Human
Tag :	MYC/DDK
Form :	25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass :	40.8 kDa
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration :	>50 ug/mL as determined by microplate BCA method

Gene Name :	IL1RAP interleukin 1 receptor accessory protein [ Homo sapiens ]
Official Symbol :	IL1RAP
Synonyms :	C3orf13; IL-1RAcP; IL1R3
Gene ID :	3556
mRNA Refseq :	NM_001167928
Protein Refseq :	NP_001161400
MIM :	602626
UniProt ID :	Q9NPH3