| Description : |
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
69.3 kDa |
| AA Sequence : |
MRGGRGAPFWLWPLPKLALLPLLWV LFQRTRPQGSAGPLQCYGVGPLGDL NCSWEPLGDLGAPSELHLQSQKYRS NKTQTVAVAAGRSWVAIPREQLTMS DKLLVWGTKAGQPLWPPVFVNLETQ MKPNAPRLGPDVDFSEDDPLEATVH WAPPTWPSHKVLICQFHYRRCQEAA WTLLEPELKTIPLTPVEIQDLELAT GYKVYGRCRMEKEEDLWGEWSPILS FQTPPSAPKDVWVSGNLCGTPGGEE PLLLWKAPGPCVQVSYKVWFWVGGR ELSPEGITCCCSLIPSGAEWARVSA VNATSWEPLTNLSLVCLDSASAPRS VAVSSIAGSTELLVTWQPGPGEPLE HVVDWARDGDPLEKLNWVRLPPGNL SALLPGNFTVGVPYRITVTAVSASG LASASSVWGFREELAPLVGPTLWRL QDAPPGTPAIAWGEVPRHQLRGHLT HYTLCAQSGTSPSVCMNVSGNTQSV TLPDLPWGPCELWVTASTIAGQGPP GPILRLHLPDNTLRWKVLPGILFLW GLFLLGCGLSLATSGRCYHLRHKVL PRWVWEKVPDPANSSSGQPHMEQVP EAQPLGDLPILEVEEMEPPPVMESS QPAQATAPLDSGYEKHFLPTPEELG LLGPPRPQVLASGPTRTRRLEQKLI SEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
