Recombinant Human IL3RA Protein (Met1-Arg305), C-His tagged
Cat.No. : | IL3RA-4278H |
Product Overview : | Recombinant human IL3RA (Met1-Arg305) fused with the C-terminal His tag was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
- Download
Description : | Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells. |
Source : | Mammalian cells |
Species : | Human |
Tag : | His |
Form : | Lyophilized powder/frozen liquid |
Molecular Mass : | 33.55 kDa |
Protein Length : | Met1-Arg305 |
Endotoxin : | < 1.0 EU/μg of the protein as determined by the LAL method. |
Purity : | >90% as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS or lyophilized from PBS. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | IL3RA interleukin 3 receptor, alpha (low affinity) [ Homo sapiens (human) ] |
Official Symbol : | IL3RA |
Synonyms : | IL3RA; interleukin 3 receptor, alpha (low affinity); interleukin-3 receptor subunit alpha; CD123; IL-3RA; IL-3R-alpha; CD123 antigen; IL-3R subunit alpha; IL-3 receptor subunit alpha; IL-3 receptor alpha SP2 isoform; IL3R; IL3RX; IL3RY; IL3RAY; hIL-3Ra; MGC34174; |
Gene ID : | 3563 |
mRNA Refseq : | NM_002183 |
Protein Refseq : | NP_002174 |
MIM : | 308385 |
UniProt ID : | P26951 |
Products Types
◆ Recombinant Protein | ||
IL3RA-06H | Recombinant Human IL3RA Protein, C-Fc-Avi tagged, Biotinylated | +Inquiry |
IL3RA-1578C | Recombinant Cynomolgus Monkey IL3RA Protein, hIgG1-tagged | +Inquiry |
IL3RA-202H | Recombinant Human IL3RA Protein (ECD), His-tagged(C-ter) | +Inquiry |
IL3RA-4517M | Recombinant Mouse IL3RA Protein, His (Fc)-Avi-tagged | +Inquiry |
IL3RA-5184H | Recombinant Human IL3RA Protein, His/Flag/StrepII-tagged | +Inquiry |
◆ Lysates | ||
IL3RA-742CCL | Recombinant Canine IL3RA cell lysate | +Inquiry |
IL3RA-2433HCL | Recombinant Human IL3RA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewIn special environment, good stability.
Good crystallization property and good effect.
Has the expected biological activity, such as enzyme activity and receptor binding activity, and so on.
Q&As (6)
Ask a questionThe feasibility of personalized therapy depends on the specific disease type and patient situation, and more research is needed to determine the application of personalized therapy to Il3ra.
Il3ra has certain promise in clinical application, especially in the treatment of immune-related diseases.
Regulates the proliferation and differentiation of immune cells by binding to its interacting cytokine IL-3, and plays a role in regulating the function of the immune system.
Clinical trials of recombinant Il3ra have been conducted in different disease areas. At present, some early trials show its potential in the treatment of certain diseases, but more research is needed to verify its efficacy and safety.
The Il3ra can regulate the proliferation and differentiation of different types of immune cells in the immune system, thus affecting the function of the immune system.
Il3ra is generally well tolerated, but some minor side effects such as headache and nausea may occur. Serious side effects are rare.
Ask a Question for All IL3RA Products
Required fields are marked with *
My Review for All IL3RA Products
Required fields are marked with *
Inquiry Basket