Recombinant Human IL3RA(Thr19-Arg305) Protein, C-Fc-Avi-tagged, Biotinylated
|Product Overview :||Recombinant Human IL3RA(P26951)(Thr19-Arg305) Protein, fused with a Fc, Avi tag at the C-terminus, was produced in HEK293. The purified protein was biotinylated in vitro.|
- Gene Information
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|Form :||Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.|
|Molecular Mass :||The recombinant Human IL3RA Protein has a predicted molecular mass of 61.8kDa, it migrates with an apparent molecular mass of 80-100kDa under reducing conditions.|
|AA Sequence :||Thr19-Arg305|
|Endotoxin :||< 0.01 EU per μg of the protein as determined by the LAL method.|
|Purity :||Greater than 95% as determined by reducing SDS-PAGE.|
|Characteristic :||The biotin to protein ratio is 0.5-1 as determined by the HABA assay.|
|Storage :||Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution :||It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 mg/ml. Centrifuge the vial at 4°C before opening to recover the entire contents.|
|Shipping :||In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
|Gene Name :||IL3RA interleukin 3 receptor, alpha (low affinity) [ Homo sapiens ]|
|Official Symbol :||IL3RA|
|Synonyms :||IL3RA; interleukin 3 receptor, alpha (low affinity); interleukin-3 receptor subunit alpha; CD123; IL-3RA; IL-3R-alpha; CD123 antigen; IL-3R subunit alpha; IL-3 receptor subunit alpha; IL-3 receptor alpha SP2 isoform; IL3R; IL3RX; IL3RY; IL3RAY; hIL-3Ra; MGC34174;|
|Gene ID :||3563|
|mRNA Refseq :||NM_002183|
|Protein Refseq :||NP_002174|
|UniProt ID :||P26951|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (6)Ask a question
The feasibility of personalized therapy depends on the specific disease type and patient situation, and more research is needed to determine the application of personalized therapy to Il3ra.
Il3ra has certain promise in clinical application, especially in the treatment of immune-related diseases.
Regulates the proliferation and differentiation of immune cells by binding to its interacting cytokine IL-3, and plays a role in regulating the function of the immune system.
Clinical trials of recombinant Il3ra have been conducted in different disease areas. At present, some early trials show its potential in the treatment of certain diseases, but more research is needed to verify its efficacy and safety.
The Il3ra can regulate the proliferation and differentiation of different types of immune cells in the immune system, thus affecting the function of the immune system.
Il3ra is generally well tolerated, but some minor side effects such as headache and nausea may occur. Serious side effects are rare.
Customer Reviews (3)Write a review
It is highly specific, that is, it binds only to its receptor IL-3R, and it has high potential in fighting disease and drug discovery -
Depending on the need, different IL-3Rα variants or mutants can be customized through techniques such as genetic modification to achieve the production of their specific properties. -
IL-3rα, by binding to its receptor, plays an important role in regulating biological processes such as cell proliferation and differentiation, and its biological activity needs to be guaranteed and can be detected by biological identification and other methods. -
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