Recombinant Human IL4R protein, His-tagged, Biotinylated
|Product Overview :||Recombinant Human IL4R protein (NP_000409.1) (Met1-His232), fused with a polyhistidine tag at the C-terminus, was expressed in HEK293 Cells. The purified protein was biotinylated in vitro.|
- Gene Information
- Related Products
|Predicted N Terminal :||Met 26|
|Form :||Lyophilized from sterile PBS, pH 7.4, 5% trehalose, 5% mannitol and 0.01% Tween80.|
|Molecular Mass :||The recombinant IL4R consists of 218 amino acids and predicts a molecular mass of 25.2 kDa.|
|Endotoxin :||< 1.0 EU per μg protein as determined by the LAL method.|
|Purity :||> 95 % as determined by SDS-PAGE.|
|Storage :||Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution :||It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 mg/ml. Centrifuge the vial at 4°C before opening to recover the entire contents.|
|Shipping :||In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.|
|Gene Name :||IL4R interleukin 4 receptor [ Homo sapiens ]|
|Official Symbol :||IL4R|
|Synonyms :||IL4R; interleukin 4 receptor; interleukin-4 receptor subunit alpha; CD124; IL-4 receptor subunit alpha; interleukin-4 receptor alpha chain; IL4RA; IL-4RA;|
|Gene ID :||3566|
|mRNA Refseq :||NM_000418|
|Protein Refseq :||NP_000409|
|UniProt ID :||P24394|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (6)Ask a question
IL4R is a synthetic protein that mimics the IL-4 signaling pathway in nature and binds to the IL-4 receptor in cells, which can be used to study the IL-4 signaling pathway and related diseases.
Common IL4R production technologies include prokaryotic expression systems and mammalian cell expression systems.
This protein is used in tumor immunotherapy, which can promote anti-tumor immune response and enhance the anti-tumor effect of cytotoxic T lymphocytes.
It is mainly used in immunology, drug research and other fields. It is also widely used in vaccines, biotechnology, cancer treatment and so on.
IL4R is used to treat severe pheochromocytome-induced aerodoritis and was approved by the FDA as the first drug to treat this disease.
IL4R cannot generally be administered orally, and needs to be administered by injection or intravenous drip.
Customer Reviews (3)Write a review
Easy to attach to the surface of cells or materials. -
It has growth factor activity to promote cell growth and proliferation. -
In animals or humans caused by the prone production of antibodies. -
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