Recombinant Human INPP5B Protein, GST-tagged

• Cat.No.: INPP5B-5106H
• Product Overview: Human INPP5B full-length ORF ( AAH58932.1, 1 a.a. - 748 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 111.4 kDa
• AA Sequence: MDQSVAIQETLAEGEYCVIAVQGVL CEGDSRQSRLLGLVRYRLEHGGQEH ALFLYTHRRMAITGDDVSLDQIVPV SRDFTLEEVSPDGELYILGSDVTVQ LDTAELSLVFQLPFGSQTRMFLHEV ARACPGFDSATRDPEFLWLSRYRCA ELELEMPTPRGCNSALVTWPGYATI GGGGSNFDGLRPNGKGVPMDQSSRG QDKPESLQPRQNKSKSEITDMVRSS TITVSDKAHILSMQKFGLRDTIVKS HLLQKEEDYTYIQNFRFFAGTYNVN GQSPKECLRLWLSNGIQAPDVYCVG FQELDLSKEAFFFHDTPKEEEWFKA VSEGLHPDAKYAKVKLIRLVGIMLL LYVKQEHAAYISEVEAETVGTGIMG RMGNKGGVAIRFQFHNTSICVVNSH LAAHIEEYERRNQDYKDICSRMQFC QPDPSLPPLTISNHDVILWLGDLNY RIEELDVEKVKKLIEEKDFQMLYAY DQLKIQVAAKTVFEGFTEGELTFQP TYKYDTGSDDWDTSEKCRAPAWCDR ILWKGKNITQLSYQSHMALKTSDHK PVSSVFDIGVRVVNDELYRKTLEEI VRSLDKMENANIPSVSLSKREFCFQ NVKYMQLKVESFTIHNGQVPCHFEF INKPDEESYCKQWLNANPSRGFLLP DSDVEIDLELFVNKTTATKLNSGED KIEDILVLHLDRGKDYFLSVSGNYL PSCFGSPIHTLCYMREPILDLPLET ISELLAYLAAYCFETQLVTKSLI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: INPP5B inositol polyphosphate-5-phosphatase, 75kDa [ Homo sapiens ]
• Official Symbol: INPP5B
• Synonyms: INPP5B; inositol polyphosphate-5-phosphatase, 75kDa; inositol polyphosphate 5 phosphatase, 75kD; type II inositol 1,4,5-trisphosphate 5-phosphatase; phosphoinositide 5-phosphatase; 75 kDa inositol polyphosphate-5-phosphatase; type II inositol-1,4,5-trisphosphate 5-phosphatase; 5PTase; MGC65156; MGC71303
• Gene ID: 3633
• mRNA Refseq: NM_005540
• Protein Refseq: NP_005531
• MIM: 147264
• UniProt ID: P32019