Recombinant Human ITGA2B Protein (639-887 aa), His-tagged
Cat.No. : | ITGA2B-1425H |
Product Overview : | Recombinant Human ITGA2B Protein (639-887 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Cardiovascular. Protein Description: Partial. |
- Specification
- Gene Information
- Related Products
Description : | Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface. |
Source : | Yeast |
Species : | Human |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 29.0 kDa |
Protein length : | 639-887 aa |
AA Sequence : | CVPQLQLTASVTGSPLLVGADNVLE LQMDAANEGEGAYEAELAVHLPQGA HYMRALSNVEGFERLICNQKKENET RVVLCELGNPMKKNAQIGIAMLVSV GNLEEAGESVSFQLQIRSKNSQNPN SKIVLLDVPVRAEAQVELRGNSFPA SLVVAAEEGEREQNSLDSWGPKVEH TYELHNNGPGTVNGLHLSIHLPGQS QPSDLLYILDIQPQGGLQCFPQPPV NPLKVDWGLPIPSPSPIHPAHHKR |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
Gene Name : | ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) [ Homo sapiens ] |
Official Symbol : | ITGA2B |
Synonyms : | ITGA2B; CD41; CD41B; GPalpha IIb; GT; GTA; GP2B; HPA3; GPIIb; BDPLT2; |
Gene ID : | 3674 |
mRNA Refseq : | NM_000419 |
Protein Refseq : | NP_000410 |
MIM : | 607759 |
UniProt ID : | P08514 |
Products Types
◆ Recombinant Protein | ||
ITGA2B-4999H | Recombinant Human ITGA2B Protein, GST-tagged | +Inquiry |
ITGA2B-2598H | Recombinant Human ITGA2B protein(751-820 aa), C-hFc & C-His-tagged | +Inquiry |
ITGA2B-2615H | Recombinant Human ITGA2B Protein, MYC/DDK-tagged | +Inquiry |
ITGA2B-2339H | Recombinant Human ITGA2B Protein, His-tagged | +Inquiry |
ITGA2B-2597H | Recombinant Human ITGA2B protein(751-820 aa), C-His-tagged | +Inquiry |
◆ Native Protein | ||
ITGA2B-10H | Native Human GPIIbIIIa | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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