Recombinant Human JOSD1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: JOSD1-1822H
• Product Overview: JOSD1 MS Standard C13 and N15-labeled recombinant protein (NP_055691) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Deubiquitinates monoubiquitinated probes (in vitro). When ubiquitinated, cleaves 'Lys-63'-linked and 'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme. May increase macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis. May enhance membrane dynamics and cell motility independently of its catalytic activity.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 23.2 kDa
• AA Sequence: MSCVPWKGDKAKSESLELPQAAPPQ IYHEKQRRELCALHALNNVFQDSNA FTRDTLQEIFQRLSPNTMVTPHKKS MLGNGNYDVNVIMAALQTKGYEAVW WDKRRDVGVIALTNVMGFIMNLPSS LCWGPLKLPLKRQHWICVREVGGAY YNLDSKLKMPEWIGGESELRKFLKH HLRGKNCELLLVVPEEVEAHQSWRT DVTRTRPLEQKLISEEDLAANDILD YKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: JOSD1 Josephin domain containing 1 [ Homo sapiens (human) ]
• Official Symbol: JOSD1
• Synonyms: JOSD1; Josephin domain containing 1; Josephin-1; KIAA0063; josephin domain-containing 1; dJ508I15.2
• Gene ID: 9929
• mRNA Refseq: NM_014876
• Protein Refseq: NP_055691
• MIM: 615323
• UniProt ID: Q15040