Recombinant Human KLK5 Protein (67-293aa), C-His tagged

• Cat.No.: KLK5-3H
• Product Overview: Recombinant human KLK5 (67-293 aa), fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Description: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.
• Source: Baculovirus
• Species: Human
• Tag: C-His
• Form: Liquid
• Molecular Mass: 26.2 kDa (236aa)
• Protein Length: 67-293 aa
• AA Sequence: ADLIINGSDCDMHTQPWQAALLLRP NQLYCGAVLVHPQWLLTAAHCRKKV FRVRLGHYSLSPVYESGQQMFQGVK SIPHPGYSHPGHSNDLMLIKLNRRI RPTKDVRPINVSSHCPSAGTKCLVS GWGTTKSPQVHFPKVLQCLNISVLS QKRCEDAYPRQIDDTMFCAGDKAGR DSCQGDSGGPVVCNGSLQGLVSWGD YPCARPNRPGVYTNLCKFTKWIQET IQANSHHHHHH
• Endotoxin: < 1 EU/μg of protein (determined by LAL method)
• Purity: > 95% by SDS-PAGE
• Applications: SDS-PAGE
• Notes: Note: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
• Storage: Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/mL (determined by absorbance at 280nm)
• Storage Buffer: Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Gene Information

• Gene Name: KLK5 kallikrein-related peptidase 5 [ Homo sapiens (human) ]
• Official Symbol: KLK5
• Synonyms: KLK5; kallikrein-related peptidase 5; kallikrein 5; kallikrein-5; KLK L2; SCTE; kallikrein-like protein 2; stratum corneum tryptic enzyme; KLKL2; KLK-L2
• Gene ID: 25818
• mRNA Refseq: NM_001077491
• Protein Refseq: NP_001070959
• MIM: 605643
• UniProt ID: Q9Y337