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Recombinant Human KPNA1 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : KPNA1-1446H
Product Overview : KPNA1 MS Standard C13 and N15-labeled recombinant protein (NP_002255) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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  • Gene Information
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Description : The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 60 kDa
AA Sequence : MTTPGKENFRLKSYKNKSLNPDEMR RRREEEGLQLRKQKREEQLFKRRNV ATAEEETEEEVMSDGGFHEAQINNM EMAPGGVITSDMIEMIFSKSPEQQL SATQKFRKLLSKEPNPPIDEVISTP GVVARFVEFLKRKENCTLQFESAWV LTNIASGNSLQTRIVIQAGAVPIFI ELLSSEFEDVQEQAVWALGNIAGDS TMYRDYVLDCNILPPLLQLFSKQNR LTMTRNAVWALSNLCRGKSPPPEFA KVSPCLNVLSWLLFVSDTDVLADAC WALSYLSDGPNDKIQAVIDAGVCRR LVELLMHNDYKVVSPALRAVGNIVT GDDIQTQVILNCSALQSLLHLLSSP KESIKKEACWTISNITAGNRAQIQT VIDANIFPALISILQTAEFRTRKEA AWAITNATSGGSAEQIKYLVELGCI KPLCDLLTVMDSKIVQVALNGLENI LRLGEQEAKRNGTGINPYCALIEEA YGLDKIEFLQSHENQEIYQKAFDLI EHYFGTEDEDSSIAPQVDLNQQQYI FQQCEAPMEGFQLTRTRPLEQKLIS EEDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : KPNA1 karyopherin subunit alpha 1 [ Homo sapiens (human) ]
Official Symbol : KPNA1
Synonyms : KPNA1; karyopherin alpha 1 (importin alpha 5); importin subunit alpha-1; IPOA5; NPI 1; RCH2; SRP1; SRP1-beta; importin alpha 5; importin-alpha-S1; RAG cohort protein 2; nucleoprotein interactor 1; karyopherin subunit alpha-1; recombination activating gene cohort 2; NPI-1;
Gene ID : 3836
mRNA Refseq : NM_002264
Protein Refseq : NP_002255
MIM : 600686
UniProt ID : P52294

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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