Recombinant Human KRT81 protein, His-tagged KRT81-1508H

Recombinant Human KRT81 protein, His-tagged

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Recombinant Human KRT81 protein, His-tagged

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Cat.No. : KRT81-1508H
Product Overview : Recombinant Human KRT81 aa. (Gln142~Thr257 (Accession # Q14533)) fused with N-terminal His tag was produced in E. coli cells.
Description : The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
Source : E. coli
Species : Human
Tag : His
Form : Freeze-dried powder
Molecular Mass : 15kDa as determined by SDS-PAGE reducing conditions.
Protein length : Gln142~Thr257 (Accession # Q14533)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Isoelectric Point : 4.9
Gene Name : KRT81 keratin 81 [ Homo sapiens (human) ]
Official Symbol : KRT81
Synonyms : KRT81; keratin 81; HB1; Hb-1; KRTHB1; MLN137; ghHkb1; hHAKB2-1; keratin, type II cuticular Hb1; K81; MLN 137; ghHb1; hair keratin K2.9; hard keratin, type II, 1; keratin 81, type II; keratin, hair, basic, 1; metastatic lymph node 137 gene protein; type II hair keratin Hb1; type-II keratin Kb21
Gene ID : 3887
mRNA Refseq : NM_002281.3
Protein Refseq : NP_002272.2
UniProt ID : Q14533

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