Recombinant Human KRT81 protein, His-tagged

Cat.No. : KRT81-1508H
Product Overview : Recombinant Human KRT81 aa. (Gln142~Thr257 (Accession # Q14533)) fused with N-terminal His tag was produced in E. coli cells.
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Description : The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
Source : E. coli
Species : Human
Tag : His
Form : Freeze-dried powder
Molecular Mass : 15kDa as determined by SDS-PAGE reducing conditions.
Protein length : Gln142~Thr257 (Accession # Q14533)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Isoelectric Point : 4.9
Gene Name : KRT81 keratin 81 [ Homo sapiens (human) ]
Official Symbol : KRT81
Synonyms : KRT81; keratin 81; HB1; Hb-1; KRTHB1; MLN137; ghHkb1; hHAKB2-1; keratin, type II cuticular Hb1; K81; MLN 137; ghHb1; hair keratin K2.9; hard keratin, type II, 1; keratin 81, type II; keratin, hair, basic, 1; metastatic lymph node 137 gene protein; type II hair keratin Hb1; type-II keratin Kb21
Gene ID : 3887
mRNA Refseq : NM_002281.3
Protein Refseq : NP_002272.2
UniProt ID : Q14533

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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