Recombinant Human MAP3K14

Cat.No. : MAP3K14-30381TH
Product Overview : Recombinant Fragment from Human MAP3K14
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
Tissue specificity : Weakly expressed in testis, small intestine, spleen, thymus, peripheral blood leukocytes, prostate, ovary and colon.
Biological activity : The protein has a GST tag.
Form : Liquid
Purity : >90% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0
Storage : Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities : Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.Contains 1 protein kinase domain.
Gene Name : MAP3K14 mitogen-activated protein kinase kinase kinase 14 [ Homo sapiens ]
Official Symbol : MAP3K14
Synonyms : MAP3K14; mitogen-activated protein kinase kinase kinase 14; FTDCR1B; HS; HSNIK; NIK; serine/threonine protein kinase;
Gene ID : 9020
mRNA Refseq : NM_003954
Protein Refseq : NP_003945
MIM : 604655
Uniprot ID : Q99558
Chromosome Location : 17q21-q22
Pathway : Adaptive Immune System, organism-specific biosystem; Alternative NF-kappaB pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; CD28 co-stimulation, organism-specific biosystem;
Function : ATP binding; MAP kinase kinase kinase activity; NF-kappaB-inducing kinase activity; nucleotide binding; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All MAP3K14 Products

Required fields are marked with *

My Review for All MAP3K14 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends