Recombinant Human MAP3K14
Cat.No. : | MAP3K14-30381TH |
Product Overview : | Recombinant Fragment from Human MAP3K14 |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. |
Tissue specificity : | Weakly expressed in testis, small intestine, spleen, thymus, peripheral blood leukocytes, prostate, ovary and colon. |
Biological activity : | The protein has a GST tag. |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0 |
Storage : | Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.Contains 1 protein kinase domain. |
Gene Name : | MAP3K14 mitogen-activated protein kinase kinase kinase 14 [ Homo sapiens ] |
Official Symbol : | MAP3K14 |
Synonyms : | MAP3K14; mitogen-activated protein kinase kinase kinase 14; FTDCR1B; HS; HSNIK; NIK; serine/threonine protein kinase; |
Gene ID : | 9020 |
mRNA Refseq : | NM_003954 |
Protein Refseq : | NP_003945 |
MIM : | 604655 |
Uniprot ID : | Q99558 |
Chromosome Location : | 17q21-q22 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Alternative NF-kappaB pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; CD28 co-stimulation, organism-specific biosystem; |
Function : | ATP binding; MAP kinase kinase kinase activity; NF-kappaB-inducing kinase activity; nucleotide binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
MAP3K14-2488R | Recombinant Rhesus Macaque MAP3K14 Protein, His (Fc)-Avi-tagged | +Inquiry |
MAP3K14-01H | Active Recombinant Human MAP3K14 Protein, GST&His-tagged | +Inquiry |
MAP3K14-894H | Active Recombinant Human MAP3K14 Protein, His/GST-tagged | +Inquiry |
MAP3K14-0627H | Recombinant Human MAP3K14 Protein (L318-P947), His/Strep tagged | +Inquiry |
MAP3K14-0626H | Recombinant Human MAP3K14 Protein (L318-P947), Tag Free | +Inquiry |
◆ Lysates | ||
MAP3K14-4507HCL | Recombinant Human MAP3K14 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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