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Recombinant Human MAP3K14
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Cat.No. : | MAP3K14-30381TH Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Fragment from Human MAP3K14 |
Description : | This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. |
Tissue specificity : | Weakly expressed in testis, small intestine, spleen, thymus, peripheral blood leukocytes, prostate, ovary and colon. |
Biological activity : | The protein has a GST tag. |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0 |
Storage : | Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.Contains 1 protein kinase domain. |
Gene Name : | MAP3K14 mitogen-activated protein kinase kinase kinase 14 [ Homo sapiens ] |
Official Symbol : | MAP3K14 |
Synonyms : | MAP3K14; mitogen-activated protein kinase kinase kinase 14; FTDCR1B; HS; HSNIK; NIK; serine/threonine protein kinase; |
Gene ID : | 9020 |
mRNA Refseq : | NM_003954 |
Protein Refseq : | NP_003945 |
MIM : | 604655 |
Uniprot ID : | Q99558 |
Chromosome Location : | 17q21-q22 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Alternative NF-kappaB pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; CD28 co-stimulation, organism-specific biosystem; |
Function : | ATP binding; MAP kinase kinase kinase activity; NF-kappaB-inducing kinase activity; nucleotide binding; protein binding; |
◆ Recombinant Protein
MAP3K14-01H | Recombinant Human MAP3K14 Protein, GST&His-tagged | +Inquiry |
MAP3K14-894H | Recombinant Human MAP3K14 Protein, His/GST-tagged | +Inquiry |
MAP3K14-2488R | Recombinant Rhesus Macaque MAP3K14 Protein, His (Fc)-Avi-tagged | +Inquiry |
MAP3K14-0627H | Recombinant Human MAP3K14 Protein (L318-P947), His/Strep tagged | +Inquiry |
MAP3K14-0626H | Recombinant Human MAP3K14 Protein (L318-P947), Tag Free | +Inquiry |
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◆ Lysates
MAP3K14-4507HCL | Recombinant Human MAP3K14 293 Cell Lysate | +Inquiry |
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MAP1LC3AMAP1LC3BMAP1LC3B2Map2k1MAP2K2MAP2K3MAP2K6Map3k1MAP3K14MAP3K2MAP3K3MAP3K5MAP3K8MAP4K5MAP2K4MAP3K6MAP2K5MAP2K7MAP3K11MAP4K4MAP4K2MAP4K1MAP1SMap2MAP3K13MAP3K15MAP3K4MAP3K7MAP3K7IP1MAP4MAP3K10MAP3K9MAP1AMAP1BMAP7MAP4K3MAP3K12MAP1LC3CMAP6D1MAP7D1MAP9MAP6MAP2K1IP1MAP7D2MAP7D3
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