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Recombinant Human MAP3K7 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : MAP3K7-4095H
Product Overview : MAP3K7 MS Standard C13 and N15-labeled recombinant protein (NP_003179) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 64 kDa
AA Sequence : MSTASAASSSSSSSAGEMIEAPSQV LNFEEIDYKEIEVEEVVGRGAFGVV CKAKWRAKDVAIKQIESESERKAFI VELRQLSRVNHPNIVKLYGACLNPV CLVMEYAEGGSLYNVLHGAEPLPYY TAAHAMSWCLQCSQGVAYLHSMQPK ALIHRDLKPPNLLLVAGGTVLKICD FGTACDIQTHMTNNKGSAAWMAPEV FEGSNYSEKCDVFSWGIILWEVITR RKPFDEIGGPAFRIMWAVHNGTRPP LIKNLPKPIESLMTRCWSKDPSQRP SMEEIVKIMTHLMRYFPGADEPLQY PCQYSDEGQSNSATSTGSFMDIAST NTSNKSDTNMEQVPATNDTIKRLES KLLKNQAKQQSESGRLSLGASRGSS VESLPPTSEGKRMSADMSEIEARIA ATTGNGQPRRRSIQDLTVTGTEPGQ VSSRSSSPSVRMITTSGPTSEKPTR SHPWTPDDSTDTNGSDNSIPMAYLT LDHQLQPLAPCPNSKESMAVFEQHC KMAQEYMKVQTEIALLLQRKQELVA ELDQDEKDQQNTSRLVQEHKKLLDE NKSLSTYYQQCKKQLEVIRSQQQKR QGTSTRRLEQKLISEEDLAANDILD YKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : MAP3K7 mitogen-activated protein kinase kinase kinase 7 [ Homo sapiens (human) ]
Official Symbol : MAP3K7
Synonyms : MAP3K7; mitogen-activated protein kinase kinase kinase 7; TAK1; MEKK7; TGF-beta activated kinase 1; TGF-beta-activated kinase 1; transforming growth factor-beta-activated kinase 1; TGF1a;
Gene ID : 6885
mRNA Refseq : NM_003188
Protein Refseq : NP_003179
MIM : 602614
UniProt ID : O43318

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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