"MAP4K1" Related Products

Recombinant Human MAP4K1 Protein, GST-tagged

Cat.No.: MAP4K1-79H
Product Overview: Recombinant full-length human HPK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: HPK1 or Hematopoietic progenitor kinase 1 is a hematopoietic cell-restricted member of the Ste20 serine/threonine kinase super family. HPK1 is also known as mitogen-activated protein kinase kinase kinase kinase 1(MAP4K1). HPK1 is a tissue-specific upstream activator of the MEKK/JNK/SAPK signaling pathway. HPK1 diminishes T cell receptor (TCR) signaling activity and T cell proliferation by phosphorylating the adaptor protein SLP-76.
Source: Insect cells
Species: Human
Tag : GST
Molecular Mass: ~121 kDa
Purity: > 70%
Applications: Kinase Assay, WB
Stability: One year at -70 centigrade from date of shipment.
Storage: Store at -70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration: 0.05 μg/μL
Storage Buffer: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, and 25% glycerol
Gene Name: MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 [ Homo sapiens (human) ]
Official Symbol: MAP4K1
Synonyms: HPK1; mitogen-activated protein kinase kinase kinase kinase 1; MAPK/ERK kinase kinase kinase 1; MEK kinase kinase 1; MEKKK 1; hematopoietic progenitor kinase 1; EC 2.7.11.1
Gene ID: 11184
mRNA Refseq: NM_007181
Protein Refseq: NP_009112
MIM: 601983
UniProt ID: Q92918

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