Recombinant Human MAP4K2
| Cat.No. : | MAP4K2-28743TH |
| Product Overview : | Recombinant full length Human Germinal Center Kinase with N-terminal proprietary tag expressed in a Baculovirus infected Sf9 cell expression system; amino acids 1-820, 125kDa. |
- Specification
- Gene Information
- Related Products
| Description : | The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. |
| Biological activity : | The Specific activity of MAP4K2-28743TH was determined to be 290 nmol/min/mg. |
| Form : | Liquid |
| Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5 |
| Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Gene Name : | MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 [ Homo sapiens ] |
| Official Symbol : | MAP4K2 |
| Synonyms : | MAP4K2; mitogen-activated protein kinase kinase kinase kinase 2; RAB8IP; BL44; GCK; |
| Gene ID : | 5871 |
| mRNA Refseq : | NM_004579 |
| Protein Refseq : | NP_004570 |
| MIM : | 603166 |
| Uniprot ID : | Q12851 |
| Chromosome Location : | 11q13.1 |
| Pathway : | Insulin Signaling, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; TNF receptor signaling pathway, organism-specific biosystem; |
| Function : | ATP binding; ATP binding; mitogen-activated protein kinase kinase kinase binding; nucleotide binding; protein binding; |
Products Types
| ◆ Recombinant Protein | ||
| MAP4K2-5338M | Recombinant Mouse MAP4K2 Protein, His (Fc)-Avi-tagged | +Inquiry |
| MAP4K2-387H | Recombinant Human MAP4K2 Protein, MYC/DDK-tagged | +Inquiry |
| Map4k2-3933M | Recombinant Mouse Map4k2 Protein, Myc/DDK-tagged | +Inquiry |
| MAP4K2-1167H | Recombinant Human MAP4K2, His & GST tagged | +Inquiry |
| MAP4K2-3782Z | Recombinant Zebrafish MAP4K2 | +Inquiry |
| ◆ Lysates | ||
| MAP4K2-626HCL | Recombinant Human MAP4K2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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