Recombinant Human MAPK1 Protein, MYC/DDK-tagged

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Recombinant Human MAPK1 Protein, MYC/DDK-tagged

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Cat.No. : MAPK1-385H
Product Overview : Recombinant human MAPK1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description : This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 41.2 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : mitogen-activated protein kinase 1 [ Homo sapiens ]
Official Symbol : MAPK1
Synonyms : ERK; ERK-2; ERK2; ERT1; MAPK2; p38; p40; p41; p41mapk; p42-MAPK; P42MAPK; PRKM1; PRKM2
Gene ID : 5594
mRNA Refseq : NM_002745.4
Protein Refseq : NP_002736.3
MIM : 176948
UniProt ID : P28482

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