Cat.No. :	MAPK9-155H
Product Overview :	Recombinant Human MAPK9(21-110 aa) fused with His/MBP tag was expressed in E. coli.
Description :	The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Source :	E. coli
Species :	Human
Tag :	His/MBP
Form :	Liquid in PBS
Protein length :	227-424 aa
Purity :	SDS-PAGE >90%
Applications :	WB Positive Control
Stability :	Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage :	Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Gene Name :	MAPK9 mitogen-activated protein kinase 9 [ Homo sapiens ]
Official Symbol :	MAPK9
Synonyms :	MAPK9; mitogen-activated protein kinase 9; PRKM9; JNK2; Jun kinase; p54a; SAPK; MAPK 9; MAP kinase 9; c-Jun kinase 2; c-Jun N-terminal kinase 2; stress-activated protein kinase 1a; stress-activated protein kinase JNK2; JNK2A; JNK2B; JNK-55; SAPK1a; JNK2BETA; p54aSAPK; JNK2ALPHA;
Gene ID :	5601
mRNA Refseq :	NM_001135044
Protein Refseq :	NP_001128516
MIM :	602896
UniProt ID :	P45984

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