Recombinant Human MFGE8 Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: MFGE8-220H
• Product Overview: MFGE8 MS Standard C13 and N15-labeled recombinant protein (NP_005919) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 42.9 kDa
• AA Sequence: MPRPRLLAALCGALLCAPSLLVALD ICSKNPCHNGGLCEEISQEVRGDVF PSYTCTCLKGYAGNHCETKCVEPLG LENGNIANSQIAASSVRVTFLGLQH WVPELARLNRAGMVNAWTPSSNDDN PWIQVNLLRRMWVTGVVTQGASRLA SHEYLKAFKVAYSLNGHEFDFIHDV NKKHKEFVGNWNKNAVHVNLFETPV EAQYVRLYPTSCHTACTLRFELLGC ELNGCANPLGLKNNSIPDKQITASS SYKTWGLHLFSWNPSYARLDKQGNF NAWVAGSYGNDQWLQVDLGSSKEVT GIITQGARNFGSVQFVASYKVAYSN DSANWTEYQDPRTGSSKIFPGNWDN HSHKKNLFETPILARYVRILPVAWH NRIALRLELLGCTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: MFGE8 milk fat globule-EGF factor 8 protein [ Homo sapiens (human) ]
• Official Symbol: MFGE8
• Synonyms: MFGE8; milk fat globule-EGF factor 8 protein; SPAG10, sperm associated antigen 10; lactadherin; BA46; EDIL1; hP47; HsT19888; MFG E8; OAcGD3S; SED1; sperm surface protein hP47; medin; sperm associated antigen 10; breast epithelial antigen BA46; O-acetyl disialoganglioside synthase; HMFG; MFGM; MFG-E8; SPAG10
• Gene ID: 4240
• mRNA Refseq: NM_005928
• Protein Refseq: NP_005919
• MIM: 602281
• UniProt ID: Q08431