| Cat.No. : |
MIB1-5316H |
| Product Overview : |
Human MIB1 partial ORF ( NP_065825, 909 a.a. - 1006 a.a.) recombinant protein with GST-tag at N-terminal. |
| Description : |
This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). [provided by RefSeq, Jun 2013] |
| Source : |
Wheat Germ |
| Species : |
Human |
| Tag : |
GST |
| Molecular Mass : |
36.52 kDa |
| AA Sequence : |
PFIMCCGGKS SEDATDDISS GNIPVLQKDK DNTNVNADVQ KLQQQLQDIK EQTMCPVCLD RLKNMIFLCG HGTCQLCGDR MSECPICRKA IERRILLY |
| Applications : |
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Quality Control Testing: : |
12.5% SDS-PAGE Stained with Coomassie Blue.
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