Recombinant Human MMP13 protein(361-430 aa), C-His-tagged

Cat.No. : MMP13-2765H
Product Overview : Recombinant Human MMP13 protein(P45452)(361-430 aa), fused with C-terminal His tag, was expressed in E. coli.
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Source : E. coli
Species : Human
Tag : C-His
Protein length : 361-430 aa
Form : 0.15 M Phosphate buffered saline
AASequence : DILEGYPKKISELGLPKEVKKISAA VHFEDTGKTLLFSGNQVWRYDDTNH IMDKDYPRLIEEDFPGIGDK
Storage : Shipped on dry ice. Avoid repeated freeze-thaw cycles. Upon receipt, 2 days when stored at 2 to 8 °C after thawing.
Up to 12 months when aliquoted and stored at -20 to -80°C.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : MMP13 matrix metallopeptidase 13 (collagenase 3) [ Homo sapiens ]
Official Symbol : MMP13
Synonyms : MMP13; matrix metallopeptidase 13 (collagenase 3); matrix metalloproteinase 13 (collagenase 3); collagenase 3; CLG3; MMP-13; MANDP1;
Gene ID : 4322
mRNA Refseq : NM_002427
Protein Refseq : NP_002418
MIM : 600108
UniProt ID : P45452

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can MMP13 be a potential therapeutic target for cancer treatment? 04/17/2023

Yes, targeting MMP13 has been explored as a potential therapeutic strategy to inhibit cancer metastasis and invasion.

Is MMP13 involved in cardiovascular diseases? 05/29/2022

Yes, MMP13 has been implicated in cardiovascular diseases by contributing to the remodeling of blood vessels and cardiac tissues.

How does MMP13 contribute to cancer progression? 11/18/2021

MMP13 facilitates tumor invasion and metastasis by breaking down the extracellular matrix and promoting the migration of cancer cells.

How is genetic variation in MMP13 associated with disease susceptibility? 03/03/2019

Certain genetic variations in the MMP13 gene have been linked to increased susceptibility to diseases such as osteoarthritis and cancer.

Are there any clinical trials targeting MMP13? 08/30/2017

Some clinical trials are investigating drugs that specifically target MMP13 in various cancer types to assess their efficacy and safety.

Customer Reviews (3)

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Reviews
12/05/2022

    Its reliability and versatility make it an essential tool for investigating MMP13 protein's expression, function, and structural characteristics.

    07/27/2020

      The use of MMP13 protein in this technique allows researchers to explore the intricate three-dimensional structure of the protein at a molecular level.

      10/13/2016

        MMP13 protein is highly recommended for researchers due to its excellent performance in WB experiments and its utility in protein electron microscopy structure analysis.

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