Recombinant Human MMP8 protein, His-tagged
Cat.No. : | MMP8-1135H |
Product Overview : | Recombinant Human MMP8 protein (Leu101~Gly467) was fused to His-tag at the N-terminus and expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | Freeze-dried powder. PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Molecular Mass : | Predicted band size: 43.2 kDa; Observed band size: 43 kDa. |
Protein length : | Leu101-Gly467 |
Endotoxin : | <1.0 EU per 1µg (determined by the LAL method) |
Purity : | > 97% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Reconstitution : | Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | MMP8 |
Official Symbol : | MMP8 |
Synonyms : | HNC; CLG1; MMP-8; PMNL-CL |
Gene ID : | 4317 |
mRNA Refseq : | NM_002424.3 |
Protein Refseq : | NP_002415.1 |
MIM : | 120355 |
UniProt ID : | P22894 |
Products Types
◆ Recombinant Protein | ||
Mmp8-1127R | Recombinant Rat Mmp8 Protein, His&SUMO-tagged | +Inquiry |
MMP8-3376R | Recombinant Rat MMP8 Protein, His (Fc)-Avi-tagged | +Inquiry |
MMP8-5437H | Recombinant Human MMP8 Protein, GST-tagged | +Inquiry |
MMP8-4454H | Recombinant Human MMP8 Protein, His (Fc)-Avi-tagged | +Inquiry |
MMP8-154H | Recombinant Human Matrix Metallopeptidase 8, Catalytic Domain | +Inquiry |
◆ Native Protein | ||
MMP8-1656H | Active Native Human MMP8 Protein | +Inquiry |
MMP8-89H | Native Human Pro-MMP-8 | +Inquiry |
◆ Lysates | ||
MMP8-2054HCL | Recombinant Human MMP8 cell lysate | +Inquiry |
MMP8-2080MCL | Recombinant Mouse MMP8 cell lysate | +Inquiry |
MMP8-001MCL | Recombinant Mouse MMP8 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe MMP8 protein interacts with a variety of signaling pathways, including TNF-α, TGF-β, Wnt, and NF-κB.
A number of inhibitors and modulators of MMP8 protein have been developed for the regulation of MMP8 activity and the treatment of related diseases.
The MMP8 protein is involved in the tissue repair and wound healing process, by degrading damaged tissue and supporting the formation of new tissue.
MMP8 protein is involved in regulating the production of inflammation-related molecules and cell infiltration, promoting the occurrence and maintenance of inflammatory response.
MMP8 protein is involved in the inflammatory and remodeling processes of post-traumatic wound healing, contributing to wound repair and tissue regeneration.
MMP8 protein plays an important role in the occurrence and progression of diseases, and studying the regulatory mechanism of MMP8 protein is helpful for the development of new drugs, such as inhibitors targeting MMP8 protein may be applied to the treatment of related diseases
Customer Reviews (3)
Write a reviewThe use of MMP8 as a catalyst can significantly increase the rate and yield of chemical reactions with impressive high catalytic efficiency.
MMP8 is really impressive, the results of every experiment are very consistent, you can see that its production process is very careful.
MMP8 are inexpensive to prepare and cost-effective, making them ideal for our study.
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