"MRC1" Related Products

Recombinant Human MRC1 protein, His-tagged

Cat.No.: MRC1-32H
Product Overview: Recombinant Human MRC1(Leu19-Lys1383 (Thr399Ala) & (Leu407Phe)) fused with His tag at C-terminal was expressed in NS0.
Source: NS0
Species: Human
Tag: His
Predicted N Terminal: Leu19
Form: Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Bio-activity: Measured by its binding ability in a functional ELISA. When Mannan is coated at 0.2 μg/mL (100 μL/well), the concentration of Recombinant Human MMR/CD206 that produces 50% of the optimal binding response is approximately 0.2-1.2 μg/mL.
Molecular Mass: Predicted Molecular Mass: 157 kDa;SDS-PAGE: 180 kDa, reducing conditions.
Protein length: Leu19-Lys1383 (Thr399Ala) & (Leu407Phe)
Endotoxin: <0.01 EU per 1 μg of the protein by the LAL method.
Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution: Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Gene Name: MRC1 mannose receptor, C type 1 [ Homo sapiens ]
Official Symbol: MRC1
Synonyms: MRC1; mannose receptor, C type 1; mannose receptor, C type 1 like 1 , MRC1L1; macrophage mannose receptor 1; bA541I19.1; CD206; CLEC13D; CLEC13DL; mannose receptor, C type 1-like 1; C-type lectin domain family 13 member D; macrophage mannose receptor 1-like protein 1; MMR; MRC1L1; MGC181940;
Gene ID: 4360
mRNA Refseq: NM_002438
Protein Refseq: NP_002429
MIM: 153618
UniProt ID: P22897
Chromosome Location: 10p13
Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing-Cross presentation, organism-specific biosystem; Class I MHC mediated antigen processing and presentation, organism-specific biosystem; Cross-presentation of soluble exogenous antigens (endosomes), organism-specific biosystem; Immune System, organism-specific biosystem; Phagosome, organism-specific biosystem;
Function: binding; mannose binding; receptor activity; sugar binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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