Active Recombinant Human MRC1 protein, His-tagged

• Cat.No.: MRC1-32H
• Product Overview: Recombinant Human MRC1(Leu19-Lys1383 (Thr399Ala) & (Leu407Phe)) fused with His tag at C-terminal was expressed in NS0.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: His
• Predicted N Terminal: Leu19
• Form: Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
• Bio-activity: Measured by its binding ability in a functional ELISA. When Mannan is coated at 0.2 μg/mL (100 μL/well), the concentration of Recombinant Human MMR/CD206 that produces 50% of the optimal binding response is approximately 0.2-1.2 μg/mL.
• Molecular Mass: Predicted Molecular Mass: 157 kDa;SDS-PAGE: 180 kDa, reducing conditions.
• Protein length: Leu19-Lys1383 (Thr399Ala) & (Leu407Phe)
• Endotoxin: <0.01 EU per 1 μg of the protein by the LAL method.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Reconstitution: Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.

Gene Information

• Gene Name: MRC1 mannose receptor, C type 1 [ Homo sapiens ]
• Official Symbol: MRC1
• Synonyms: MRC1; mannose receptor, C type 1; mannose receptor, C type 1 like 1 , MRC1L1; macrophage mannose receptor 1; bA541I19.1; CD206; CLEC13D; CLEC13DL; mannose receptor, C type 1-like 1; C-type lectin domain family 13 member D; macrophage mannose receptor 1-like protein 1; MMR; MRC1L1; MGC181940
• Gene ID: 4360
• mRNA Refseq: NM_002438
• Protein Refseq: NP_002429
• MIM: 153618
• UniProt ID: P22897
• Chromosome Location: 10p13
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing-Cross presentation, organism-specific biosystem; Class I MHC mediated antigen processing and presentation, organism-specific biosystem; Cross-presentation of soluble exogenous antigens (endosomes), organism-specific biosystem; Immune System, organism-specific biosystem; Phagosome, organism-specific biosystem
• Function: binding; mannose binding; receptor activity; sugar binding