Active Recombinant Human MUC16 Protein, His-tagged

• Cat.No.: MUC16-42H
• Product Overview: Recombinant Human CA125/MUC16 protein Met13360-Gln14347 (Met13472Thr & Gln13957Lys) protein with a C-terminal 6-His tag expressed in CHO.

Specification

• Source: CHO
• Species: Human
• Tag: His
• Predicted N Terminal: Met13360
• Form: Lyophilized from a 0.2 μm filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA. When Recombinant Human CA125/MUC16 is coated at 1 μg/mL (100 μL/well), the concentration of Recombinant Human Galectin‑3 that produces 50% of the optimal binding response is found to be approximately 0.35-1.4 μg/mL.
• Molecular Mass: 110 kDa
• Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
• Purity: >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
• Storage: Avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
  3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Reconstitution: Reconstitute at 250 μg/mL in PBS.

Gene Information

• Gene Name: MUC16
• Official Symbol: MUC16 mucin 16, cell surface associated [ Homo sapiens (human) ]
• Synonyms: MUC16; mucin 16, cell surface associated; CA125; mucin-16; CA125 ovarian cancer antigen; ovarian cancer-related tumor marker CA125; ovarian carcinoma antigen CA125; CA-125; CA125MUC-16; FLJ14303; MUC16; mucin 16, cell surface associated; mucin-16; Ovarian cancer-related tumor marker CA125; Ovarian carcinoma antigen CA125
• Gene ID: 94025
• mRNA Refseq: NM_024690
• Protein Refseq: NP_078966
• MIM: 606154
• UniProt ID: Q8WXI7