Recombinant Human MVB12B Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | MVB12B-3689H |
Product Overview : | FAM125B MS Standard C13 and N15-labeled recombinant protein (NP_001011703) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 24.5 kDa |
AA Sequence : | MRSCFCVRRSRDPPPPQPPPPPPQR GTDQSTMPEVKDLSEALPETSMDPI TGVGVVASRNRAPTGYDVVAQTADG VDADLWKDGLFKSKVTRYLCFTRSF SKENSHLGNVLVDMKLIDIKDTLPV GFIPIQETVDTQEVAFRKKRLCIKF IPRDSTEAAICDIRIMGRTKQAPPQ YTFIGELNSMGIWYRMGRVPRNHDS SQPTTPSQSSAASTPAPNLPRTRTR PLEQKLISEEDLAANDILDYKDDDD KV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | MVB12B multivesicular body subunit 12B [ Homo sapiens (human) ] |
Official Symbol : | MVB12B |
Synonyms : | MVB12B; multivesicular body subunit 12B; C9orf28; FAM125B; multivesicular body subunit 12B; ESCRT-I complex subunit MVB12B; family with sequence similarity 125, member B |
Gene ID : | 89853 |
mRNA Refseq : | NM_001011703 |
Protein Refseq : | NP_001011703 |
UniProt ID : | Q9H7P6 |
Products Types
◆ Recombinant Protein | ||
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MVB12B-3694H | Recombinant Human MVB12B Protein, GST-tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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