Recombinant Human MVB12B Protein, MYC/DDK-tagged
Cat.No. : | MVB12B-2337H |
Product Overview : | Recombinant human MVB12B protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293 |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 24.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | MVB12B multivesicular body subunit 12B [ Homo sapiens ] |
Official Symbol : | MVB12B |
Synonyms : | C9orf28; FAM125B |
Gene ID : | 89853 |
mRNA Refseq : | NM_001011703.2 |
Protein Refseq : | NP_001011703 |
Products Types
◆ Recombinant Protein | ||
MVB12B-3694H | Recombinant Human MVB12B Protein, GST-tagged | +Inquiry |
Mvb12b-4228M | Recombinant Mouse Mvb12b Protein, Myc/DDK-tagged | +Inquiry |
MVB12B-2381C | Recombinant Chicken MVB12B | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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