Recombinant Human MX1 Protein, His-tagged

• Cat.No.: MX1-2467H
• Product Overview: Recombinant Human MX1 Protein (Ser80-Leu342) with a N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 30.3 kDa
  Accurate Molecular Mass: 34 kDa
• Protein length: Ser80-Leu342
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 95%
• Applications: Cell culture; Activity Assays.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) [ Homo sapiens (human) ]
• Official Symbol: MX1
• Synonyms: MX1; myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse); myxovirus (influenza) resistance 1, homolog of murine (interferon inducible protein p78); interferon-induced GTP-binding protein Mx1; IFI 78K; MxA; myxoma resistance protein 1; interferon-regulated resistance GTP-binding protein MxA; MX; IFI78; IFI-78K
• Gene ID: 4599
• mRNA Refseq: NM_001144925
• Protein Refseq: NP_001138397
• MIM: 147150
• UniProt ID: P20591